ADHDgene Database

SNP Report

Basic Info

Name	rs835616 dbSNP Ensembl
Location	Chr5:174863690(Fwd)
Variant Alleles	A/G/C
Ancestral Allele	A
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000393752; ENST00000329144)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases, M., 2012			genotypic P-value=0.026, genotype 11 vs 12+22: P-value=0.007...... genotypic P-value=0.026, genotype 11 vs 12+22: P-value=0.0072, OR (95% CI)=1.53 (1.12-2.09); genotype 11 +12 vs. 22: P-value=0.23, OR (95% CI)=-; allelic P-value=0.0086, OR (95% CI)=1.37 (1.09-1.75) More...	Four SNPs in DRD1 displayed nominal associations with ADHD i...... Four SNPs in DRD1 displayed nominal associations with ADHD in the childhood dataset More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DRD1	dopamine receptor D1	5q34-q35	8(5/3/0)

SNPs in LD with rs835616 (count: 3) View in gBrowse (chr5:174863690..174880514 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs265981	5_prime_UTR_variant; upstream_gene_variant	2(1/1/0)	1.0[LWK]

rs_ID	Functional Annotation	r²[population]
rs267417	upstream_gene_variant	0.83[CHB]
rs265978	downstream_gene_variant	0.863[CHB]; 0.884[GIH]