ADHDgene Database

SNP Report

Basic Info

Name	rs265981 dbSNP Ensembl
Location	Chr5:174870902(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	5_prime_UTR_variant; upstream_gene_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000393752) upstream_gene_variant(ENST00000329144)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Bobb AJ, 2005			allelic TDT P-value=0.008, OR=1.61 in case-control analysis;...... allelic TDT P-value=0.008, OR=1.61 in case-control analysis; allelic TDT P-value=0.27, RR=1.31 in family-based analysis More...	ADHD probands were more likely than controls to have the A a...... ADHD probands were more likely than controls to have the A allele More...	Significant
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DRD1	dopamine receptor D1	5q34-q35	8(5/3/0)

SNPs in LD with rs265981 (count: 11) View in gBrowse (chr5:174863690..174891621 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs686	3_prime_UTR_variant	2(1/1/0)	0.959[CEU]; 1.0[CHB]; 0.956[CHD]; 0.976[GIH]; 1.0[JPT]; 0.977[TSI]
rs835616	downstream_gene_variant	1(1/0/0)	1.0[LWK]
rs4532	5_prime_UTR_variant	1(1/0/0)	0.82[ASW]; 1.0[CEU]; 1.0[CHB]; 0.956[CHD]; 0.952[GIH]; 1.0[JPT]; 0.944[MEX]; 1.0[TSI]