ADHDgene Database

SNP Report

Basic Info

Name	rs7955501 dbSNP Ensembl
Location	Chr12:72350026(Fwd)
Variant Alleles	T/A
Ancestral Allele	T
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000546576) intron_variant(ENST00000333850; ENST00000546576)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Johansson S, 2010			logistic regression P-value=0.23, OR=1.12 logistic regression P-value=0.23, OR=1.12	no significant association no significant association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TPH2	tryptophan hydroxylase 2	12q15	10(7/3/0)

SNPs in LD with rs7955501 (count: 37) View in gBrowse (chr12:72343863..72407477 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1023990	intron_variant	1(0/1/0)	0.91[JPT]
rs1843809	NMD_transcript_variant; intron_variant	5(3/2/0)	0.896[YRI]
rs10879352	intron_variant	1(1/0/0)	0.873[CEU]
rs1386491	downstream_gene_variant; intron_variant	1(0/1/0)	0.862[JPT]
rs7305115	synonymous_variant	1(0/1/0)	0.915[CEU]

rs_ID	Functional Annotation	r²[population]
rs9325202	intron_variant	0.873[CEU]
rs4760817	intron_variant	0.917[CEU]
rs10879346	NMD_transcript_variant; intron_variant	0.921[CEU]
rs7969114	intron_variant	0.913[CEU]
rs17110532	intron_variant	0.904[JPT]
rs1843811	intron_variant	0.877[CEU]
rs17110540	intron_variant	0.855[JPT]
rs11179039	intron_variant	0.842[CEU]
rs10879351	intron_variant	0.842[CEU]
rs6582073	intron_variant	0.917[CEU]
rs17110489	NMD_transcript_variant; intron_variant	0.951[JPT]
rs17110536	intron_variant	0.855[JPT]
rs2171363	downstream_gene_variant; intron_variant	0.917[CEU]
rs10879345	NMD_transcript_variant; intron_variant	0.917[CEU]
rs7963720	intron_variant	0.917[CEU]
rs4641528	intron_variant	0.917[CEU]
rs10506645	intron_variant	0.906[JPT]
rs2368049	intron_variant	0.832[CEU]
rs7979770	intron_variant	0.92[CEU]
rs7309686	intron_variant	0.917[CEU]
rs7967686	intron_variant	0.911[CEU]
rs6582078	intron_variant	0.836[CEU]
rs17110627	intron_variant	0.863[JPT]
rs4760750	intron_variant	0.871[CEU]
rs6582077	intron_variant	0.915[CEU]
rs4760816	intron_variant	0.917[CEU]
rs4760755	intron_variant	0.917[CEU]
rs1386498	intron_variant	0.816[CEU]
rs4760754	intron_variant	0.917[CEU]
rs17110477	NMD_transcript_variant; intron_variant	1.0[JPT]
rs3903502	intron_variant	0.873[CEU]
rs12322900	NMD_transcript_variant; intron_variant	0.919[CEU]