ADHDgene Database

SNP Report

Basic Info

Name	rs40358 dbSNP Ensembl
Location	Chr5:1416142(Fwd)
Variant Alleles	C/A
Ancestral Allele	A
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000513308) intron_variant(ENST00000511750; ENST00000453492; ENST00000270349) nc_transcript_variant(ENST00000511750)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Shang CY, 2011	T/G		T allele FBAT P-value=0.157, Z=1.414 for total sample; T all...... T allele FBAT P-value=0.157, Z=1.414 for total sample; T allele FBAT P-value=0.054, Z=1.93 for combined subtype; T allele FBAT P-value=0.637, Z=0.471 for inattentive subtype More...	no significant associations in the total sample; displayed a...... no significant associations in the total sample; displayed a trend for association in combined subtype More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)

SNPs in LD with rs40358 (count: 7) View in gBrowse (chr5:1416142..1438354 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs37020	intron_variant; upstream_gene_variant	2(1/1/0)	0.949[JPT]; 0.905[YRI]
rs403636	intron_variant	3(1/2/0)	0.939[CEU]; 0.869[GIH]; 0.896[JPT]
rs464049	intron_variant	1(0/1/0)	0.948[JPT]; 0.863[YRI]