ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs3813034 dbSNP Ensembl
Location	Chr17:28524804(Fwd)
Variant Alleles	A/C
Ancestral Allele	A
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000261707; ENST00000401766) downstream_gene_variant(ENST00000578609; ENST00000394821; ENST00000579221)
No. of Studies	4 (significant: 0; non-significant: 4; trend: 0)
Source	Literature-origin

SNP related studies (count: 4)

Reference	Allele Change	Statistical Values	Author Comments	Result of Statistical Analysis
Banerjee E, 2009	G689T	HHRR P-value=0.902; TDT P-value=0.23; pooled TDT P-value=0.4...... HHRR P-value=0.902; TDT P-value=0.23; pooled TDT P-value=0.47 More...	This polymorphism is not associated with risk of ADHD. This polymorphism is not associated with risk of ADHD.	Non-significant
Gizer IR, 2009		Meta-analysis model: Random: OR=1.05, 95% CI=0.87-1.26, P-va...... Meta-analysis model: Random: OR=1.05, 95% CI=0.87-1.26, P-value=0.304; Q-statistic: P-value=0.222, I²=30 More...	no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More...	Non-significant
Wigg KG, 2006	T/G	TDT P-value=0.941, X²=0.006 TDT P-value=0.941, X²=0.006	no evidence of biased transmission no evidence of biased transmission	Non-significant
Heiser P, 2007	A/C	allelic PDT P-value=0.46 allelic PDT P-value=0.46	showed no statistically significant preferential transmissio...... showed no statistically significant preferential transmission of any allele More...	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	17q11.2	25(13/12/0)

Genes from other sources (count: 0)

SNPs in LD with rs3813034 (count: 86) View in gBrowse (chr17:28328819..28550732 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 6)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs140701	intron_variant; upstream_gene_variant	3(1/2/0)	1.0[CHD]; 0.92[JPT]; 0.866[TSI]
rs1042173	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	1(0/1/0)	0.92[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.938[LWK]; 0.955[MEX]; 1.0[TSI]; 1.0[YRI]
rs4325622	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(1/0/0)	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs11080121	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(1/0/0)	0.961[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs4583306	intron_variant; upstream_gene_variant	1(1/0/0)	0.92[JPT]; 0.866[TSI]
rs1979572	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant	1(1/0/0)	0.961[CEU]; 1.0[CHB]; 1.0[JPT]

LD-proxies (count: 80)

rs_ID	Functional Annotation	r²[population]
rs8071742	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 0.866[GIH]; 0.912[MEX]; 0.954[TSI]
rs4343336	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.916[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.966[LWK]; 1.0[MEX]; 0.893[MKK]; 1.0[TSI]; 1.0[YRI]
rs9912741	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 0.866[GIH]; 0.912[MEX]; 0.954[TSI]
rs7221743	intron_variant; synonymous_variant	0.961[CEU]; 0.819[GIH]; 1.0[MEX]; 0.954[TSI]
rs7220151	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.961[CEU]
rs9896012	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.924[CEU]; 1.0[CHB]; 1.0[CHD]; 0.932[GIH]; 1.0[JPT]; 0.83[MEX]; 0.808[TSI]
rs4528633	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.889[CEU]; 0.87[MEX]
rs9906340	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.961[CEU]; 0.864[GIH]; 1.0[MEX]; 0.954[TSI]
rs3794808	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHD]; 0.92[JPT]; 0.822[MEX]; 0.842[TSI]
rs4465650	NMD_transcript_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	0.961[CEU]; 0.841[GIH]; 0.828[MEX]; 0.931[TSI]
rs4470197	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 1.0[CHB]; 1.0[JPT]
rs4533341	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 0.977[TSI]
rs8065059	downstream_gene_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 0.931[CHB]; 0.956[CHD]; 0.932[GIH]; 1.0[MEX]; 0.977[TSI]
rs8080343	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.961[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.915[JPT]; 0.87[MEX]; 0.954[TSI]
rs9902340	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.924[CEU]; 1.0[CHB]; 1.0[CHD]; 0.932[GIH]; 1.0[JPT]; 0.83[MEX]; 0.808[TSI]
rs7216631	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 0.896[JPT]
rs17825877	downstream_gene_variant	0.916[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.967[LWK]; 1.0[MEX]; 0.893[MKK]; 0.977[TSI]; 1.0[YRI]
rs9898353	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 1.0[CHB]; 1.0[JPT]
rs4350617	downstream_gene_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 0.931[CHB]; 0.956[CHD]; 0.954[GIH]; 0.85[JPT]; 1.0[MEX]; 0.977[TSI]
rs4356528	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs4074170	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; synonymous_variant; upstream_gene_variant	0.961[CEU]
rs7222685	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs11653805	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.887[CEU]
rs12948898	intron_variant; upstream_gene_variant	0.889[CEU]; 0.87[MEX]
rs4427857	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.924[CEU]; 1.0[CHB]; 1.0[JPT]
rs7218379	downstream_gene_variant; intron_variant	0.889[CEU]; 0.867[MEX]
rs4795529	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.889[CEU]; 0.931[CHB]; 0.956[CHD]; 0.885[GIH]; 0.85[JPT]; 0.87[MEX]; 0.803[TSI]
rs8082175	intron_variant; nc_transcript_variant	0.961[CEU]; 0.931[CHB]; 0.956[CHD]; 0.954[GIH]; 0.85[JPT]; 1.0[MEX]; 0.977[TSI]
rs1906451	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs11080115	intron_variant	0.889[CEU]; 0.87[MEX]
rs11080114	intron_variant	0.961[CEU]; 0.819[GIH]; 1.0[MEX]; 0.954[TSI]
rs7212292	intron_variant; upstream_gene_variant	0.889[CEU]
rs12939344	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.889[CEU]; 0.87[MEX]
rs9303628	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.924[CEU]; 1.0[CHB]; 0.956[CHD]; 0.931[GIH]; 1.0[JPT]; 0.808[TSI]
rs11080118	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.924[CEU]; 1.0[CHB]; 1.0[CHD]; 0.931[GIH]; 1.0[JPT]; 0.806[TSI]
rs12103671	intron_variant	0.889[CEU]; 0.87[MEX]
rs6505158	downstream_gene_variant; intron_variant	0.961[CEU]; 0.866[GIH]; 1.0[MEX]; 0.954[TSI]
rs4239227	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 1.0[MEX]; 0.954[TSI]
rs4328498	NMD_transcript_variant; intron_variant	0.961[CEU]; 0.866[GIH]; 0.955[MEX]; 0.954[TSI]
rs6505162	5_prime_UTR_variant; NMD_transcript_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.835[ASW]; 0.81[CEU]; 0.931[CHB]; 0.956[CHD]; 0.885[GIH]; 0.85[JPT]; 0.867[MEX]; 0.846[YRI]
rs7223786	NMD_transcript_variant; intron_variant	0.961[CEU]; 0.866[GIH]; 1.0[MEX]; 0.954[TSI]
rs9900974	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.889[CEU]; 0.87[MEX]
rs4075623	NMD_transcript_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 1.0[MEX]; 0.954[TSI]
rs4429345	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.916[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.905[LWK]; 0.955[MEX]; 1.0[TSI]; 1.0[YRI]
rs7217638	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 0.912[MEX]; 0.954[TSI]
rs4294864	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.961[CEU]; 0.856[CHB]; 0.85[JPT]
rs7212497	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 1.0[MEX]; 0.954[TSI]
rs9904336	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.96[CEU]
rs9908901	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 1.0[CHB]; 1.0[JPT]
rs9905950	intron_variant; nc_transcript_variant	0.887[CEU]; 0.93[CHB]; 0.84[JPT]
rs7213517	downstream_gene_variant; intron_variant	0.889[CEU]; 0.87[MEX]
rs7225686	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.889[CEU]; 0.87[MEX]
rs2054846	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs7211246	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.959[CEU]; 1.0[CHB]; 1.0[JPT]
rs7213076	downstream_gene_variant; intron_variant; nc_transcript_variant	0.887[CEU]; 0.931[CHB]; 0.956[CHD]; 0.885[GIH]; 0.87[MEX]; 0.803[TSI]
rs9896062	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 1.0[MEX]; 0.954[TSI]
rs12449783	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[JPT]
rs12602065	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs34585141	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.865[MEX]
rs7207021	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.961[CEU]; 0.866[GIH]; 0.954[MEX]; 0.954[TSI]
rs7217961	downstream_gene_variant; intron_variant	0.889[CEU]; 0.87[MEX]
rs4575590	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.96[CEU]
rs8074028	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.87[MEX]; 0.954[TSI]
rs4547389	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.889[CEU]; 0.87[MEX]
rs10853136	downstream_gene_variant; intron_variant	0.902[CEU]
rs9902453	NMD_transcript_variant; intron_variant	0.961[CEU]; 0.86[GIH]; 1.0[MEX]; 0.954[TSI]
rs12941382	intron_variant; upstream_gene_variant	0.887[CEU]; 0.867[MEX]
rs4493117	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.923[CEU]; 1.0[CHB]; 1.0[JPT]
rs7221154	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.864[MEX]; 0.954[TSI]
rs8065261	intron_variant; nc_transcript_variant	0.961[CEU]; 0.931[CHB]; 0.956[CHD]; 0.954[GIH]; 1.0[MEX]; 0.977[TSI]
rs7224199	3_prime_UTR_variant; downstream_gene_variant	0.961[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.865[MEX]; 0.954[TSI]
rs7219456	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.889[CEU]; 0.87[MEX]
rs4581755	intron_variant; nc_transcript_variant	0.961[CEU]; 0.931[CHB]; 0.956[CHD]; 0.954[GIH]; 0.85[JPT]; 1.0[MEX]; 0.977[TSI]
rs9890205	NMD_transcript_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 0.912[MEX]; 0.954[TSI]
rs9900911	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.961[CEU]; 0.864[GIH]; 0.955[MEX]; 0.954[TSI]
rs2020939	intron_variant	0.83[TSI]
rs9890886	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.961[CEU]; 0.866[GIH]; 0.955[MEX]; 0.954[TSI]
rs2054847	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]; 0.92[JPT]
rs12450441	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs7220004	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.889[CEU]; 0.87[MEX]