ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs10258145 dbSNP Ensembl
Location	Chr7:34599721(Fwd)
Variant Alleles	G/A
Ancestral Allele	A
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000419766; ENST00000537560; ENST00000539747) nc_transcript_variant(ENST00000419766; ENST00000537560; ENST00000539747)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	A:G		GLM P-value=3.58E-05, meta-analysis P-value=0.3281 GLM P-value=3.58E-05, meta-analysis P-value=0.3281	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
NPSR1-AS1	NPSR1 antisense RNA 1	7p14.3

SNPs in LD with rs10258145 (count: 50) View in gBrowse (chr7:21106269..34696545 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 4)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1023556	intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	0.83[CEU]; 0.931[GIH]; 0.81[MEX]; 0.849[TSI]
rs6462569	intron_variant; nc_transcript_variant	1(0/1/0)	1.0[CEU]; 0.905[CHD]; 1.0[GIH]; 0.805[JPT]; 0.834[LWK]; 0.952[MEX]; 0.905[MKK]; 1.0[TSI]; 0.84[YRI]
rs12690808	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	1(0/1/0)	0.883[ASW]; 1.0[CEU]; 0.869[CHB]; 0.953[CHD]; 1.0[GIH]; 0.805[JPT]; 0.975[LWK]; 1.0[MEX]; 0.961[MKK]; 1.0[TSI]; 0.919[YRI]
rs2893482	intron_variant; nc_transcript_variant	1(0/1/0)	1.0[CEU]; 0.869[CHB]; 0.953[CHD]; 1.0[GIH]; 0.805[JPT]; 0.829[LWK]; 0.903[MEX]; 0.903[MKK]; 1.0[TSI]; 0.84[YRI]

LD-proxies (count: 46)

rs_ID	Functional Annotation	r²[population]
rs10245758	intron_variant; nc_transcript_variant	0.8[GIH]
rs2609238	downstream_gene_variant; intron_variant; nc_transcript_variant	0.882[CEU]; 0.906[GIH]
rs10245143	intron_variant; nc_transcript_variant	0.909[TSI]
rs2108735	downstream_gene_variant; intron_variant; nc_transcript_variant	0.872[YRI]
rs13438112	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.867[CHB]; 0.805[JPT]; 0.881[YRI]
rs17169889	intron_variant; nc_transcript_variant	0.877[CEU]; 0.849[JPT]
rs1362202	intron_variant; nc_transcript_variant	1.0[CEU]; 0.869[CHB]; 0.805[JPT]; 0.878[YRI]
rs6955780	intron_variant; nc_transcript_variant	0.815[CEU]
rs6462568	intron_variant; nc_transcript_variant	0.806[YRI]
rs6955901	intron_variant; nc_transcript_variant	0.824[CEU]
rs10272610	intron_variant; nc_transcript_variant	0.94[CEU]; 0.869[CHB]; 0.805[JPT]; 0.878[YRI]
rs11976127	intron_variant; nc_transcript_variant	0.818[CEU]; 0.86[CHB]; 0.802[JPT]; 0.802[YRI]
rs2392273	intron_variant; nc_transcript_variant	0.869[CHB]; 0.93[CHD]; 0.845[GIH]; 0.805[JPT]; 0.81[MEX]
rs12672538	intron_variant; nc_transcript_variant	0.826[CEU]; 0.878[CHD]; 0.804[GIH]; 0.849[JPT]
rs10245221	intron_variant; nc_transcript_variant	0.909[TSI]
rs12701367	intron_variant; nc_transcript_variant	0.877[CEU]; 0.805[JPT]
rs17169876	intron_variant; nc_transcript_variant	0.802[YRI]
rs10241719	intron_variant; nc_transcript_variant	0.8[GIH]
rs2097960	downstream_gene_variant; intron_variant; nc_transcript_variant	0.82[GIH]; 0.81[MEX]
rs2190897	intron_variant; nc_transcript_variant	0.881[CEU]
rs17169893	intron_variant; nc_transcript_variant	0.82[GIH]
rs7778336	intron_variant; nc_transcript_variant	0.802[CEU]; 0.907[CHB]; 0.847[JPT]
rs10239558	downstream_gene_variant; intron_variant; nc_transcript_variant	0.878[YRI]
rs10951422	intron_variant; nc_transcript_variant	0.807[CEU]
rs1023555	intron_variant; nc_transcript_variant; upstream_gene_variant	0.83[CEU]
rs10951419	intron_variant; nc_transcript_variant	0.942[CEU]; 0.866[CHB]; 0.802[JPT]; 0.948[YRI]
rs10486649	intron_variant; nc_transcript_variant	0.826[CEU]; 0.869[CHB]; 0.953[CHD]; 0.845[GIH]; 0.805[JPT]; 0.81[MEX]
rs11982356	intron_variant; nc_transcript_variant	0.804[GIH]
rs1419774	downstream_gene_variant; intron_variant; nc_transcript_variant	0.819[GIH]; 0.81[MEX]
rs17169871	intron_variant; nc_transcript_variant	0.852[TSI]
rs10243426	downstream_gene_variant; intron_variant; nc_transcript_variant	0.82[GIH]; 0.8[MEX]
rs6962591	intron_variant; nc_transcript_variant	1.0[CEU]; 0.869[CHB]; 0.805[JPT]; 0.919[YRI]
rs4141269	intron_variant; nc_transcript_variant	0.882[CEU]
rs10229982	intron_variant; nc_transcript_variant	0.82[GIH]; 0.81[MEX]
rs10231845	intron_variant; nc_transcript_variant	1.0[CEU]; 0.902[CHB]; 0.805[JPT]; 0.919[YRI]
rs740515	intron_variant; nc_transcript_variant	0.826[CEU]; 0.869[CHB]; 0.952[CHD]; 0.845[GIH]; 0.857[MEX]
rs1981606	intron_variant; nc_transcript_variant	0.877[CEU]; 0.805[JPT]
rs7781421	intron_variant; nc_transcript_variant	0.88[TSI]; 0.84[YRI]
rs2392274	intron_variant; nc_transcript_variant	0.82[GIH]; 0.81[MEX]
rs740514	intron_variant; nc_transcript_variant	0.826[CEU]; 0.834[CHD]; 0.845[GIH]; 0.805[JPT]; 0.858[MEX]
rs10277729	feature_elongation; intron_variant; nc_transcript_variant	0.87[CEU]
rs13229729	intron_variant; nc_transcript_variant	0.877[CEU]; 0.869[CHB]; 0.805[JPT]
rs11976817	intron_variant; nc_transcript_variant	0.826[CEU]; 0.808[YRI]
rs990878	intron_variant; nc_transcript_variant	0.804[GIH]
rs10261506	intron_variant; nc_transcript_variant	0.824[CEU]
rs2079509	downstream_gene_variant; intron_variant; nc_transcript_variant	0.82[GIH]; 0.81[MEX]