ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	B4GALT6
Symbol Alias	beta4GalT-VI
Approved Name	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
Name Alias	UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase
Location	18q11
Position	chr18:29202209-29264686, -
External Links	HGNC: 929 Entrez Gene: 9331 Ensembl: ENSG00000118276 UCSC: uc002kwz.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 14)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0042339	keratan sulfate metabolic process	Biological Process		9
GO:0032580	Golgi cisterna membrane	Cellular Component		18
GO:0044267	cellular protein metabolic process	Biological Process		64
GO:0043687	post-translational protein modification	Biological Process		37
GO:0046872	metal ion binding	Molecular Function		170
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0000139	Golgi membrane	Cellular Component		95
GO:0005975	carbohydrate metabolic process	Biological Process		50
GO:0008378	galactosyltransferase activity	Molecular Function	TAS[9597550]	3
GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	Molecular Function		1
GO:0016021	integral to membrane	Cellular Component		845
GO:0018146	keratan sulfate biosynthetic process	Biological Process		8
GO:0018279	protein N-linked glycosylation via asparagine	Biological Process		24
GO:0030203	glycosaminoglycan metabolic process	Biological Process		20

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00600	Sphingolipid metabolism	10
hsa01100	Metabolic pathways	237

Genes shared at least 5 GO terms with B4GALT6 (count: 24)

Gene Symbol	Pathway Count	Pathway List
B4GALT4	13	keratan sulfate metabolic process; Golgi cisterna membrane; cellular protein metabolic process; post-translational protein modification; metal ion binding; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; galactosyltransferase activity; integral to membrane; keratan sulfate biosynthetic process; protein N-linked glycosylation via asparagine; glycosaminoglycan metabolic process;
ST3GAL4	10	keratan sulfate metabolic process; Golgi cisterna membrane; cellular protein metabolic process; post-translational protein modification; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; keratan sulfate biosynthetic process; protein N-linked glycosylation via asparagine; glycosaminoglycan metabolic process;
CHST5	7	keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process;
CHST6	7	keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process;
CHPF	7	Golgi cisterna membrane; metal ion binding; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;
MGAT1	7	cellular protein metabolic process; post-translational protein modification; metal ion binding; Golgi membrane; carbohydrate metabolic process; integral to membrane; protein N-linked glycosylation via asparagine;
B3GNT1	6	keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process;
LMAN1	6	cellular protein metabolic process; post-translational protein modification; metal ion binding; Golgi membrane; integral to membrane; protein N-linked glycosylation via asparagine;
MAN2A2	6	cellular protein metabolic process; post-translational protein modification; Golgi membrane; carbohydrate metabolic process; integral to membrane; protein N-linked glycosylation via asparagine;
MGAT4B	6	cellular protein metabolic process; post-translational protein modification; metal ion binding; Golgi membrane; integral to membrane; protein N-linked glycosylation via asparagine;
B3GAT1	6	metal ion binding; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;
GALNS	5	keratan sulfate metabolic process; metal ion binding; small molecule metabolic process; carbohydrate metabolic process; glycosaminoglycan metabolic process;
OGN	5	keratan sulfate metabolic process; small molecule metabolic process; carbohydrate metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process;
OMD	5	keratan sulfate metabolic process; small molecule metabolic process; carbohydrate metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process;
GALNT1	5	Golgi cisterna membrane; cellular protein metabolic process; post-translational protein modification; Golgi membrane; integral to membrane;
B3GNT6	5	cellular protein metabolic process; post-translational protein modification; Golgi membrane; galactosyltransferase activity; integral to membrane;
FURIN	5	cellular protein metabolic process; post-translational protein modification; metal ion binding; Golgi membrane; integral to membrane;
MAN1A1	5	cellular protein metabolic process; post-translational protein modification; Golgi membrane; integral to membrane; protein N-linked glycosylation via asparagine;
STS	5	cellular protein metabolic process; post-translational protein modification; metal ion binding; small molecule metabolic process; integral to membrane;
B3GAT3	5	small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;
CHST9	5	small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;
DSE	5	small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;
HS3ST2	5	small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;
HS3ST5	5	small molecule metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process;

Genes shared at least 2 KEGG pathways with B4GALT6 (count: 7)

Gene Symbol	Pathway Count	Pathway List
ENPP7	2	Sphingolipid metabolism; Metabolic pathways;
SMPD1	2	Sphingolipid metabolism; Metabolic pathways;
SMPD2	2	Sphingolipid metabolism; Metabolic pathways;
SMPD4	2	Sphingolipid metabolism; Metabolic pathways;
SPTLC1	2	Sphingolipid metabolism; Metabolic pathways;
SPTLC3	2	Sphingolipid metabolism; Metabolic pathways;
UGCG	2	Sphingolipid metabolism; Metabolic pathways;

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Region: chr18:29202209..29264686 View in gBrowse