ADHDgene Database

SNP Report

Basic Info

Name	rs9659997 dbSNP Ensembl
Location	Chr1:20002518(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000289753)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2009(b)			Case-control test: lowest P-value=0.023 for genotype analysi...... Case-control test: lowest P-value=0.023 for genotype analysis, P-value=0.0055 for allele analysis in all adult ADHD; lowest P-value=0.028 for genotype analysis, P-value=0.031 for allele analysis in adult inattentive ADHD. More...	no significance after correcting for multiple comparisons no significance after correcting for multiple comparisons	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR6	5-hydroxytryptamine (serotonin) receptor 6	1p36-p35	2(0/2/0)

SNPs in LD with rs9659997 (count: 15) View in gBrowse (chr1:19987294..20020994 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs4515815	missense_variant; nc_transcript_variant; non_coding_exon_variant	0.907[CEU]
rs7543480	feature_truncation; intron_variant; nc_transcript_variant	1.0[CEU]; 0.857[CHB]; 0.844[CHD]; 0.952[TSI]
rs10917517	intron_variant; nc_transcript_variant	1.0[CEU]; 0.857[CHB]
rs1883565	downstream_gene_variant	1.0[CEU]; 0.857[CHB]; 0.847[CHD]; 0.976[TSI]
rs4912141	intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.89[LWK]; 1.0[MEX]; 0.889[MKK]; 1.0[TSI]; 1.0[YRI]
rs6693503	downstream_gene_variant; upstream_gene_variant	0.881[ASW]; 1.0[CEU]; 0.821[CHD]; 0.931[GIH]; 0.804[LWK]; 0.976[TSI]; 0.828[YRI]
rs10917509	5_prime_UTR_variant	0.881[ASW]; 1.0[CEU]; 0.821[CHD]; 0.977[GIH]; 0.804[LWK]; 1.0[TSI]; 0.828[YRI]
rs10917513	downstream_gene_variant	1.0[CEU]; 0.924[CHB]; 0.937[CHD]; 0.845[GIH]; 0.976[TSI]
rs3748749	downstream_gene_variant; intron_variant; nc_transcript_variant	0.824[CEU]
rs10159394	intron_variant; nc_transcript_variant	0.911[CEU]; 0.86[TSI]
rs4912018	downstream_gene_variant; intron_variant; nc_transcript_variant	0.829[CEU]
rs2050121	downstream_gene_variant; intron_variant; nc_transcript_variant	0.819[CEU]; 0.835[TSI]
rs7533981	intron_variant; nc_transcript_variant	1.0[CEU]; 0.857[CHB]; 0.877[CHD]; 0.952[TSI]
rs10917518	downstream_gene_variant; intron_variant; nc_transcript_variant	0.816[CEU]
rs7527271	intron_variant; nc_transcript_variant	1.0[CEU]; 0.857[CHB]; 0.847[CHD]; 0.952[TSI]