ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs7683787 dbSNP Ensembl
Location	Chr4:91830629(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	NMD_transcript_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000505073; ENST00000513522; ENST00000509109) intron_variant(ENST00000509176; ENST00000505073; ENST00000513522; ENST00000503421; ENST00000333691; ENST00000509109; ENST00000515693) nc_transcript_variant(ENST00000515693)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lantieri F, 2010			TDT P-value=E-05 TDT P-value=E-05	a level of significance only reached by a total of five SNPs...... a level of significance only reached by a total of five SNPs in this genome-wide data More...	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
FAM190A	family with sequence similarity 190, member A	4q22.1	1(1/0/0)

Genes from other sources (count: 0)

SNPs in LD with rs7683787 (count: 17) View in gBrowse (chr4:91826328..91856308 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 2)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1551773	NMD_transcript_variant; intron_variant; nc_transcript_variant	1(0/0/1)	0.963[GIH]; 0.928[TSI]
rs11097273	NMD_transcript_variant; intron_variant; nc_transcript_variant	1(0/0/1)	0.928[ASW]; 1.0[CHB]; 0.972[CHD]; 1.0[GIH]; 0.949[JPT]; 0.885[LWK]; 0.985[MKK]; 0.953[TSI]; 1.0[YRI]

LD-proxies (count: 15)

rs_ID	Functional Annotation	r²[population]
rs7683403	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.804[CEU]
rs6824383	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]; 0.951[YRI]
rs13135875	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.961[GIH]; 0.807[JPT]; 0.928[TSI]
rs10012191	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.963[GIH]; 0.928[TSI]
rs17249857	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.917[CEU]; 0.953[CHB]; 1.0[JPT]
rs2061015	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.814[JPT]
rs7657375	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.917[CEU]; 1.0[CHB]; 0.945[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[TSI]
rs28643477	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.806[CEU]; 0.818[TSI]
rs6855137	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.804[CEU]
rs7660952	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.804[CEU]
rs11097277	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.915[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs7683238	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.804[CEU]
rs1993748	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.804[CEU]; 1.0[YRI]
rs11097271	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.804[CEU]; 0.929[GIH]
rs6532253	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.837[CEU]; 0.929[GIH]