ADHDgene Database

SNP Report

Basic Info

Name	rs7577925 dbSNP Ensembl
Location	Chr2:134040519(Fwd)
Variant Alleles	G/A
Ancestral Allele	A
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000409261; ENST00000358991; ENST00000409213; ENST00000427594; ENST00000317721; ENST00000405974; ENST00000432414) nc_transcript_variant(ENST00000432414)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008			P-value=2.55E-06 under Dominant model for FBAT-PC all sympto...... P-value=2.55E-06 under Dominant model for FBAT-PC all symptoms More...	association finding with P-value association finding with P-value	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
NCKAP5	NCK-associated protein 5	2q21.2	1(0/0/1)

SNPs in LD with rs7577925 (count: 9) View in gBrowse (chr2:133999831..134046163 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs1985935	downstream_gene_variant; intron_variant; nc_transcript_variant	0.898[CHB]; 1.0[JPT]
rs1549739	downstream_gene_variant; intron_variant	0.94[ASW]; 0.809[CHB]; 0.939[GIH]; 1.0[JPT]; 0.977[LWK]; 0.822[MEX]; 0.934[MKK]; 0.875[TSI]; 1.0[YRI]
rs1344726	downstream_gene_variant; intron_variant	0.94[ASW]; 0.977[LWK]; 0.822[MEX]; 0.855[MKK]; 0.877[TSI]; 0.853[YRI]
rs2115866	intron_variant	0.83[LWK]
rs1430170	intron_variant; nc_transcript_variant	0.898[CHB]; 0.94[GIH]; 1.0[JPT]; 0.807[MKK]
rs7568471	intron_variant	0.815[YRI]
rs6430407	intron_variant; nc_transcript_variant	0.878[ASW]; 1.0[CEU]; 0.947[CHB]; 1.0[CHD]; 0.888[GIH]; 1.0[JPT]; 1.0[MEX]; 0.842[MKK]; 0.95[TSI]
rs1367207	intron_variant; nc_transcript_variant	0.957[CEU]; 0.947[CHB]; 1.0[JPT]; 0.858[YRI]
rs4057049	intron_variant; upstream_gene_variant	0.874[LWK]; 0.924[YRI]