ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs727605 dbSNP Ensembl
Location	Chr16:9955564(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000396573; ENST00000566683; ENST00000396575; ENST00000330684; ENST00000562109; ENST00000535259; ENST00000404927) nc_transcript_variant(ENST00000566683)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Adams J, 2004	G/A	A	ETDT P-value=0.94; FBAT P-value=0.47 for stop-task; FBAT P-v...... ETDT P-value=0.94; FBAT P-value=0.47 for stop-task; FBAT P-value=0.94 for digit span forwards; FBAT P-value=0.68 for digit span backwards More...	No evidence for biased transmission of alleles, no significa...... No evidence for biased transmission of alleles, no significant evidence for a relationship between the transmission of alleles and scores of the three cognitive phenotypes. More...	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	16p13.2	3(1/2/0)

Genes from other sources (count: 0)

SNPs in LD with rs727605 (count: 59) View in gBrowse (chr16:9880781..9996580 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 2)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs8049651	downstream_gene_variant; synonymous_variant	1(0/1/0)	0.828[CEU]; 0.939[GIH]; 0.932[MEX]; 0.957[YRI]
rs12920919	intron_variant	1(0/1/0)	1.0[CHB]; 1.0[CHD]; 0.882[GIH]; 0.888[JPT]; 0.932[MEX]

LD-proxies (count: 57)

rs_ID	Functional Annotation	r²[population]
rs7196095	intron_variant	0.863[CEU]
rs7189901	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.911[YRI]
rs2299934	intron_variant	0.869[CEU]
rs11639526	intron_variant	0.869[CEU]; 0.846[TSI]
rs917834	intron_variant; nc_transcript_variant	1.0[CEU]; 0.864[CHB]; 0.888[JPT]
rs9933832	intron_variant; nc_transcript_variant	0.955[CEU]; 1.0[CHB]; 1.0[CHD]; 0.969[GIH]; 0.888[JPT]; 0.934[MEX]; 0.897[TSI]
rs11647369	intron_variant; nc_transcript_variant	0.8[MEX]
rs7195942	intron_variant	0.869[CEU]; 0.821[TSI]
rs7204928	intron_variant; nc_transcript_variant	0.864[CHB]; 1.0[CHD]; 0.888[JPT]; 0.847[TSI]
rs9932138	intron_variant	0.806[MEX]
rs2077923	intron_variant	0.869[CEU]; 0.846[TSI]
rs2299933	intron_variant	0.862[CEU]
rs5003769	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.888[JPT]
rs9926912	intron_variant; nc_transcript_variant	0.828[CEU]
rs16966529	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.888[JPT]; 0.957[YRI]
rs2267795	intron_variant; nc_transcript_variant	0.888[JPT]
rs2284237	intron_variant	0.83[CEU]
rs11648283	intron_variant	0.869[CEU]
rs8058295	intron_variant	0.849[GIH]
rs9926303	downstream_gene_variant; intron_variant	0.825[CEU]; 1.0[CHB]; 0.888[JPT]
rs9934477	downstream_gene_variant; intron_variant	0.952[CEU]; 1.0[CHB]; 0.888[JPT]
rs6497524	intron_variant	0.828[CEU]
rs9972744	intron_variant	0.862[CEU]
rs16966381	intron_variant	0.869[CEU]; 0.872[TSI]
rs17793917	intron_variant	0.849[GIH]
rs9940694	intron_variant; nc_transcript_variant	0.828[CEU]
rs11647877	intron_variant	0.849[GIH]; 0.865[MEX]
rs8050843	intron_variant	0.849[GIH]; 0.865[MEX]
rs6497523	intron_variant	0.849[GIH]; 0.827[TSI]
rs2267792	intron_variant	0.83[CEU]; 0.849[GIH]; 0.864[TSI]
rs2267787	intron_variant	0.869[CEU]
rs1544606	intron_variant	0.855[CEU]
rs9302396	intron_variant; nc_transcript_variant	0.864[CHB]; 0.888[JPT]
rs2215718	downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[CHD]; 0.88[GIH]; 0.888[JPT]; 0.865[MEX]; 0.848[TSI]
rs16951624	intron_variant; nc_transcript_variant	0.888[JPT]
rs7196023	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.887[JPT]; 0.956[YRI]
rs7204266	intron_variant; nc_transcript_variant	0.927[CHD]; 0.888[JPT]
rs7196708	intron_variant	0.849[GIH]
rs9922678	intron_variant; nc_transcript_variant	0.869[CEU]; 1.0[CHB]; 0.888[JPT]
rs9928908	intron_variant; nc_transcript_variant	0.888[JPT]
rs8063193	intron_variant; nc_transcript_variant	0.881[ASW]; 0.955[CEU]; 1.0[CHB]; 0.969[GIH]; 0.888[JPT]; 0.939[MKK]; 0.895[TSI]; 1.0[YRI]
rs7199375	intron_variant; nc_transcript_variant	1.0[CEU]; 0.846[CHB]; 0.957[YRI]
rs1861192	intron_variant	0.849[GIH]
rs7201930	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.888[JPT]; 0.934[MEX]; 0.949[TSI]
rs11642764	intron_variant	0.879[GIH]
rs1544604	intron_variant	0.869[CEU]; 0.821[TSI]
rs9938117	intron_variant	0.879[GIH]; 0.864[MEX]
rs1004936	intron_variant; nc_transcript_variant	0.828[CEU]
rs12934281	intron_variant	0.849[GIH]
rs2010691	intron_variant; nc_transcript_variant	0.869[CEU]
rs1833161	intron_variant	0.869[CEU]; 0.821[TSI]
rs9674103	intron_variant	0.846[GIH]
rs7203268	intron_variant; nc_transcript_variant	0.907[YRI]
rs11642239	intron_variant; nc_transcript_variant	0.825[ASW]
rs9302397	intron_variant; nc_transcript_variant	0.864[CHB]; 1.0[CHD]; 0.888[JPT]; 0.874[TSI]
rs16966631	intron_variant; nc_transcript_variant	0.8[MEX]
rs2267791	intron_variant	0.828[CEU]