ADHDgene Database

SNP Report

Basic Info

Name	rs6350 dbSNP Ensembl
Location	Chr5:1443199(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	synonymous_variant; upstream_gene_variant.
Consequence to Transcript	synonymous_variant(ENST00000453492; ENST00000270349) upstream_gene_variant(ENST00000513308)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant
Friedel S, 2007	C/T	C	FAMHAP P-value=0.008 in single marker association analysis FAMHAP P-value=0.008 in single marker association analysis	not significantly associated with ADHD after multiple test c...... not significantly associated with ADHD after multiple test correction More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)

SNPs in LD with rs6350 (count: 2) View in gBrowse (chr5:1443199..1460132 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs11564757	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.895[GIH]; 1.0[JPT]; 1.0[MEX]; 0.834[TSI]
rs2937652	NMD_transcript_variant; downstream_gene_variant; intron_variant	1.0[CHB]