ADHDgene Database

SNP Report

Basic Info

Name	rs602618 dbSNP Ensembl
Location	Chr10:112843085(Fwd)
Variant Alleles	C/A
Ancestral Allele	C
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000280155)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	A:C	A	P-value=0.8864, X²=0.02, OR=1.02, 95% CI=0.77-1.3...... P-value=0.8864, X²=0.02, OR=1.02, 95% CI=0.77-1.34 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)

SNPs in LD with rs602618 (count: 14) View in gBrowse (chr10:112686323..112856425 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs521674	upstream_gene_variant	1(0/1/0)	0.95[CEU]; 1.0[CHB]; 1.0[JPT]

rs_ID	Functional Annotation	r²[population]
rs11195400	intron_variant; nc_transcript_variant	0.825[CEU]; 0.864[TSI]
rs638019	upstream_gene_variant	0.947[CHB]; 1.0[JPT]
rs10885077	intron_variant; nc_transcript_variant	1.0[YRI]
rs12416020	downstream_gene_variant	1.0[CEU]
rs1327551	intron_variant; nc_transcript_variant	0.825[CEU]; 0.954[YRI]
rs10885068	intron_variant; nc_transcript_variant	0.825[CEU]; 0.816[JPT]
rs10787294	intron_variant; nc_transcript_variant	0.883[YRI]
rs4918613	downstream_gene_variant; intron_variant; nc_transcript_variant	0.823[CEU]; 0.807[TSI]
rs7908645		0.83[CHD]; 0.837[JPT]
rs10885079		1.0[CEU]; 0.956[GIH]; 0.865[TSI]
rs7079511	intron_variant; nc_transcript_variant	0.825[CEU]; 0.867[MEX]; 0.878[MKK]; 0.865[TSI]; 0.866[YRI]
rs10885070	downstream_gene_variant; intron_variant; nc_transcript_variant	0.816[CEU]; 0.819[MEX]; 0.907[MKK]; 0.863[TSI]; 0.866[YRI]
rs745557		0.853[CHD]; 0.836[JPT]