ADHDgene Database

SNP Report

Basic Info

Name	rs2000292 dbSNP Ensembl
Location	Chr6:78166945(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ickowicz A, 2007	G/A	A	TDT P-value=0.615 TDT P-value=0.615	No evidence for biased transmission No evidence for biased transmission	Non-significant
Smoller JW, 2006	C/T		allelic P-value=0.022 in inattentive; allelic P-value=0.21 i...... allelic P-value=0.022 in inattentive; allelic P-value=0.21 in ADHD; allelic P-value=0.74 in combined More...	displayed nominally significant association with the inatten...... displayed nominally significant association with the inattentive subtype More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	6q13	13(5/8/0)

SNPs in LD with rs2000292 (count: 4) View in gBrowse (chr6:78166945..78228544 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs6296	synonymous_variant	10(3/7/0)	0.907[TSI]
rs6298	synonymous_variant	4(0/4/0)	0.907[TSI]

rs_ID	Functional Annotation	r²[population]
rs1303712		0.814[CEU]
rs10806098	upstream_gene_variant	0.828[CEU]; 0.849[TSI]