ADHDgene Database

SNP Report

Basic Info

Name	rs140700 dbSNP Ensembl
Location	Chr17:28543389(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000401766; ENST00000394821; ENST00000261707)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Landaas ET, 2010	A/G		P-value=0.011, OR=0.67 in the Norwegian samples; P-value=0.0...... P-value=0.011, OR=0.67 in the Norwegian samples; P-value=0.00084, OR=0.45 in the Norwegian samples; P-value=0.68, OR=0.92 in the Norwegian males; meta-analysis P-value=0.20, OR=0.85 for A allele More...	showed an association between rs140700 and ADHD in the Norwe...... showed an association between rs140700 and ADHD in the Norwegian sample, and this association was mainly restricted to females; but the the meta-analysis did not support the association More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	17q11.2	25(13/12/0)

SNPs in LD with rs140700 (count: 3) View in gBrowse (chr17:28457049..28552773 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs11080122	intron_variant	0.888[JPT]
rs8071667	intron_variant	0.887[JPT]
rs11650871	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]