ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

SNP Report

Basic Info

Name	rs12861247 dbSNP Ensembl
Location	ChrX:7174199(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000217961)
No. of Studies	3 (significant: 2; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes KJ, 2008(b)			TDT P-value=0.0055, OR=2.05; Bonferroni correction P-value=0...... TDT P-value=0.0055, OR=2.05; Bonferroni correction P-value=0.0385; P-value=0.015 for males only More...	remains significant after correction; significantly associat...... remains significant after correction; significantly associated with male probands More...	Significant
Brookes KJ, 2010			TDT P-value=0.01, OR=1.88 TDT P-value=0.01, OR=1.88	was previously genotyped and still significant in this large...... was previously genotyped and still significant in this larger sample but cannot survive stringent correction for multiple testing; also associated with reduced STS mRNA expression in normal human post-mortem frontal cortex brain tissue compared to the non-risk allele (P-value=0.01) More...	Significant
Stergiakouli E, 2011	G/A		P-value=0.762, OR=1.08 in the total sample of case-control a...... P-value=0.762, OR=1.08 in the total sample of case-control analysis; P-value=0.888, OR=0.96 in males only More...	there was no significant difference between cases and contro...... there was no significant difference between cases and controls More...	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources (count: 0)

SNPs in LD with rs12861247 (count: 0) View in gBrowse (chrX:7174199..7174199 )