ADHDgene Database

SNP Report

Basic Info

Name	rs10762524 dbSNP Ensembl
Location	Chr10:53773912(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000373985; ENST00000373980; ENST00000373976; ENST00000401604)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	T:G		GLM P-value=9.89E-07, meta-analysis P-value=0.3336 GLM P-value=9.89E-07, meta-analysis P-value=0.3336	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PRKG1	protein kinase, cGMP-dependent, type I	10q11.2	1(0/0/1)

SNPs in LD with rs10762524 (count: 13) View in gBrowse (chr10:53734733..53790034 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs10762539	intron_variant	1(0/1/0)	0.905[CHB]
rs7901487	intron_variant	1(0/1/0)	0.905[CHB]
rs10823964	intron_variant	1(0/0/1)	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.977[GIH]; 1.0[JPT]; 0.88[MEX]; 0.815[TSI]
rs10762540	intron_variant	1(0/1/0)	0.905[CHB]
rs10823973	intron_variant	1(0/0/1)	1.0[CEU]; 1.0[CHB]; 0.974[CHD]; 0.977[GIH]; 0.859[JPT]; 0.977[TSI]