ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs1051730 dbSNP Ensembl
Location	Chr15:78894339(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	NMD_transcript_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000559658) nc_transcript_variant(ENST00000558903) non_coding_exon_variant(ENST00000558903) synonymous_variant(ENST00000348639; ENST00000326828; ENST00000559658)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Thakur G. A., 2012	C/T	T	FBAT: Z=-1.52, P=0.13, effect size=0.12 FBAT: Z=-1.52, P=0.13, effect size=0.12	No association with ADHD was found. No association with ADHD was found.	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CHRNA3	cholinergic receptor, nicotinic, alpha 3	15q24	1(0/1/0)

Genes from other sources (count: 0)

SNPs in LD with rs1051730 (count: 44) View in gBrowse (chr15:78724469..79085915 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 44)

rs_ID	Functional Annotation	r²[population]
rs12899135	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs12914385	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.924[CEU]; 0.935[GIH]; 0.838[MEX]; 0.832[TSI]
rs16969920	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.817[YRI]
rs11630236	downstream_gene_variant; missense_variant; upstream_gene_variant	1.0[JPT]
rs2036527		0.961[CEU]; 0.905[GIH]; 1.0[JPT]; 0.941[MEX]; 0.886[TSI]
rs12902602	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs17483929	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.809[CEU]
rs17484524	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.802[CEU]; 1.0[JPT]
rs951266	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.966[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.935[MKK]; 0.93[TSI]; 1.0[YRI]
rs16969968	downstream_gene_variant; intron_variant; missense_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.941[MEX]; 0.954[TSI]
rs9788721	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.961[CEU]; 0.814[GIH]; 0.838[MEX]
rs11631955	intron_variant; nc_transcript_variant	1.0[JPT]
rs7174367	intron_variant; nc_transcript_variant	1.0[JPT]
rs11072785	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs1317286	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]
rs2568494	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.809[CEU]
rs4887077	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs2656052	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.809[CEU]
rs1021071	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs1809420	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[JPT]
rs10519203	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.961[CEU]; 0.876[GIH]; 0.887[MEX]; 0.8[TSI]
rs8034191	NMD_transcript_variant; intron_variant	0.961[CEU]; 0.9[GIH]; 1.0[JPT]; 0.941[MEX]; 0.8[TSI]
rs17487223	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.81[CEU]; 1.0[CHB]; 0.828[CHD]
rs11638372	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs1394371		1.0[JPT]
rs2656065	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.8[CEU]
rs17486278	intron_variant	1.0[CEU]
rs7180002	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs922692	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs1996371	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs11638830	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CHB]
rs11634351	NMD_transcript_variant; intron_variant	1.0[CHB]
rs1504550	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant	0.809[CEU]; 1.0[JPT]
rs17405217	NMD_transcript_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.809[CEU]; 1.0[JPT]
rs2277550	intron_variant	1.0[CHD]; 1.0[JPT]
rs2009746	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.802[CEU]
rs8031948	NMD_transcript_variant; intron_variant	0.96[CEU]; 1.0[JPT]
rs17484235	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.809[CEU]; 1.0[JPT]
rs17483548	intron_variant; upstream_gene_variant	0.809[CEU]; 1.0[JPT]
rs931794	downstream_gene_variant; intron_variant; upstream_gene_variant	0.961[CEU]
rs8040868	5_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant	0.888[CEU]; 0.876[GIH]
rs7181486	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.809[CEU]
rs11639372	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs17483721	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.809[CEU]