ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs10268637 dbSNP Ensembl
Location Chr7:114074257(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation NMD_transcript_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript NMD_transcript_variant(ENST00000412402; ENST00000441290; ENST00000440349)
intron_variant(ENST00000412402; ENST00000441290; ENST00000440349; ENST00000324462; ENST00000393498; ENST00000408937; ENST00000350908; ENST00000462331; ENST00000393494; ENST00000393489; ENST00000360232; ENST00000378237; ENST00000459666; ENST00000390668; ENST00000403559; ENST00000393500; ENST00000393495; ENST00000452963)
nc_transcript_variant(ENST00000459666)
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Ribases, M., 2012 P-value=0.114 in 643 adult attention-deficit/hyperactivity d...... P-value=0.114 in 643 adult attention-deficit/hyperactivity disorder patients and and 619 unrelated controls from Germany; P-value=0.046, OR (95% CI)=1.20 (1.00-1.44) in 431 combined attention-deficit/hyperactivity disorder patients and 619 unrelated controls from Germany More... The single-marker study under a log additive model showed no...... The single-marker study under a log additive model showed no evidence of an association between FOXP2 and adulthood ADHD when the overall sample or the combined and inattentive types of ADHD from Spain were considered (data not shown). The SNP reached statistical significance in the German combinedtype ADHD group. More... Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs10268637 (count: 24) View in gBrowse (chr7:114015707..114147217 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 2)

LD-proxies (count: 22)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014