ADHDgene Database

SNP Report

Basic Info

Name	rs1014531 dbSNP Ensembl
Location	Chr16:9855794(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000396573) downstream_gene_variant(ENST00000396575; ENST00000562109; ENST00000463531; ENST00000330684; ENST00000461292; ENST00000404927; ENST00000535259) upstream_gene_variant(ENST00000562861)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Adams J, 2004	G/A	A	ETDT P-value=0.36; FBAT P-value=0.92 for stop-task; FBAT P-v...... ETDT P-value=0.36; FBAT P-value=0.92 for stop-task; FBAT P-value=0.14 for digit span forwards; FBAT P-value=0.29 for digit span backwards More...	No evidence for biased transmission of alleles, no significa...... No evidence for biased transmission of alleles, no significant evidence for a relationship between the transmission of alleles and scores of the three cognitive phenotypes. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	16p13.2	3(1/2/0)

SNPs in LD with rs1014531 (count: 15) View in gBrowse (chr16:9801207..9873939 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2267770	intron_variant; upstream_gene_variant	1(0/1/0)	0.922[CEU]; 1.0[CHB]; 1.0[CHD]; 0.901[GIH]; 1.0[JPT]

rs_ID	Functional Annotation	r²[population]
rs11644075	intron_variant; upstream_gene_variant	0.812[CEU]
rs7197214	intron_variant; upstream_gene_variant	0.922[CEU]; 0.928[CHB]; 1.0[CHD]; 0.935[GIH]; 1.0[JPT]; 0.911[MEX]; 0.825[TSI]
rs8060992	intron_variant	0.96[CEU]; 0.863[CHB]; 0.858[CHD]; 1.0[JPT]; 0.831[MEX]; 0.818[TSI]
rs10852236		0.826[CEU]; 0.9[CHB]
rs7184228		0.96[CEU]; 0.85[CHB]; 0.935[GIH]; 1.0[MEX]; 0.977[TSI]
rs7202950	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs7196878	intron_variant; upstream_gene_variant	0.922[CEU]; 0.923[CHB]; 1.0[JPT]
rs11866328	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.962[CHD]; 0.905[GIH]; 1.0[JPT]; 0.908[MEX]; 0.911[TSI]
rs12928053		0.845[CEU]; 0.85[CHB]
rs11639516		0.85[CHB]; 1.0[MEX]; 0.908[TSI]
rs11642978		0.848[CEU]
rs10852235		0.886[CHB]
rs7190895	intron_variant; upstream_gene_variant	0.919[CEU]; 0.928[CHB]; 1.0[JPT]
rs7196797	intron_variant; upstream_gene_variant	0.922[CEU]; 0.915[CHB]; 1.0[JPT]