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- Data Summary
GO Report
Basic Info
| ID | GO:0006184 |
|---|---|
| Name | GTP catabolic process |
| Type | Biological Process |
| No. of Genes in ADHDgene | 22 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 22)
Literature-origin genes (count: 5)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | 1p13 | 1(1/0/0) | |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 16q13 | 1(0/1/0) | TAS[1899283] |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | 18p11.22-p11.21 | 1(1/0/0) | TAS[8243272] |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | 22q11.1-q11.2 | 1(0/1/0) | TAS[2117645] |
| DNM1 | dynamin 1 | 9q34 | 1(0/0/1) | TAS[10944110] |
Genes from other sources (count: 17)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | Mapped by significant region | TAS[7665596] |
| RAB6C | RAB6C, member RAS oncogene family | Mapped by significant region | IDA[10455022] |
| RAB38 | RAB38, member RAS oncogene family | Mapped by significant region | NAS[10910072] |
| ARL2 | ADP-ribosylation factor-like 2 | Mapped by significant region | IMP[10831612] |
| ARF6 | ADP-ribosylation factor 6 | Mapped by PBA pathway | TAS[1993656] |
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | Mapped by PBA pathway | TAS[9233818] |
| RAB2A | RAB2A, member RAS oncogene family | Mapped by PBA pathway | IDA[16034420]; TAS[2501306] |
| RAB14 | RAB14, member RAS oncogene family | Mapped by PBA pathway; Mapped by significant region | IDA[16034420]; NAS[15004230] |
| MTG1 | mitochondrial GTPase 1 homolog (S. cerevisiae) | Mapped by CNV | |
| OPA1 | optic atrophy 1 (autosomal dominant) | Mapped by CNV | TAS[11017080] |
| ATL3 | atlastin GTPase 3 | Mapped by significant region | NAS[18270207] |
| SEPT5 | septin 5 | Mapped by CNV | TAS[9385360] |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 | Mapped by significant region | TAS[10075696] |
| ARHGAP5 | Rho GTPase activating protein 5 | Mapped by significant region | TAS[8537347] |
| RAB6A | RAB6A, member RAS oncogene family | Mapped by CNV; Mapped by significant region | IDA[18243103]; TAS[2501306] |
| RAB30 | RAB30, member RAS oncogene family | Mapped by significant region | TAS[9792283] |
| RHOD | ras homolog gene family, member D | Mapped by significant region | TAS[9116026] |