ADHDgene Database

Gene Report

Basic Info

Approved Symbol	UBXN1
Symbol Alias	LOC51035, 2B28, UBXD10, SAKS1
Approved Name	UBX domain protein 1
Name Alias	SAPK substrate protein 1
Location	11q23
Position	chr11:62443970-62446567, -
External Links	HGNC: 18402 Entrez Gene: 51035 Ensembl: ENSG00000162191 UCSC: uc001nuj.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0071796	K6-linked polyubiquitin binding	Molecular Function		1
GO:0051117	ATPase binding	Molecular Function	IPI[15362974]	7
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	Biological Process	NAS[15362974]	16
GO:0043130	ubiquitin binding	Molecular Function	IDA[18775313]	9
GO:0043025	neuronal cell body	Cellular Component		51
GO:0034098	Cdc48p-Npl4p-Ufd1p AAA ATPase complex	Cellular Component	IDA[18775313]	1
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological Process		1
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IDA[18775313]	23
GO:0031593	polyubiquitin binding	Molecular Function	IDA[15362974]	4
GO:0031397	negative regulation of protein ubiquitination	Biological Process		5
GO:0030425	dendrite	Cellular Component		46
GO:0005737	cytoplasm	Cellular Component	IDA[10942595]	690
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function		910
GO:0000502	proteasome complex	Cellular Component	IDA[15362974]	14

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with UBXN1 (count: 6)

Gene Symbol	Pathway Count	Pathway List
ARRB1	6	proteasomal ubiquitin-dependent protein catabolic process; ubiquitin protein ligase binding; negative regulation of protein ubiquitination; cytoplasm; nucleus; protein binding;
ARRB2	6	proteasomal ubiquitin-dependent protein catabolic process; ubiquitin protein ligase binding; negative regulation of protein ubiquitination; cytoplasm; nucleus; protein binding;
RAD23B	6	proteasomal ubiquitin-dependent protein catabolic process; polyubiquitin binding; cytoplasm; nucleus; protein binding; proteasome complex;
TNFAIP3	5	ubiquitin binding; negative regulation of protein ubiquitination; cytoplasm; nucleus; protein binding;
GSK3B	5	neuronal cell body; ubiquitin protein ligase binding; cytoplasm; nucleus; protein binding;
STRN3	5	neuronal cell body; dendrite; cytoplasm; nucleus; protein binding;

Genes shared at least 2 KEGG pathways with UBXN1 (count: 0)

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Region: chr11:62443970..62446567 View in gBrowse