ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SETMAR
Symbol Alias	metnase
Approved Name	SET domain and mariner transposase fusion gene
Location	3p26.2
Position	chr3:4344988-4359251, +
External Links	HGNC: 10762 Entrez Gene: 6419 Ensembl: ENSG00000170364 UCSC: uc011asp.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_15	chr3:2969491-4461303 (NCBI Build 36.1 (hg18))	1538470	3p26.3-3p26.2	Loss
CNV_Williams[2010]_9	chr3:3999657-4922174 (NCBI Build 36.1 (hg18))	922518	3p26.2	Gain	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 16)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0008270	zinc ion binding	Molecular Function		323
GO:0015074	DNA integration	Biological Process		5
GO:0018024	histone-lysine N-methyltransferase activity	Molecular Function		4
GO:0042803	protein homodimerization activity	Molecular Function		113
GO:0005515	protein binding	Molecular Function	IPI[19390626]	910
GO:0005634	nucleus	Cellular Component		770
GO:0005694	chromosome	Cellular Component		15
GO:0006313	transposition, DNA-mediated	Biological Process	TAS[9461395]	1
GO:0043566	structure-specific DNA binding	Molecular Function		1
GO:0071157	negative regulation of cell cycle arrest	Biological Process	IMP[19390626]	3
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	Biological Process		1
GO:2001251	negative regulation of chromosome organization	Biological Process		1
GO:0000737	DNA catabolic process, endonucleolytic	Biological Process		1
GO:0000729	DNA double-strand break processing	Biological Process		1
GO:0004803	transposase activity	Molecular Function		1
GO:0004519	endonuclease activity	Molecular Function		7

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00310	Lysine degradation	9

Genes shared at least 5 GO terms with SETMAR (count: 0)

Genes shared at least 2 KEGG pathways with SETMAR (count: 0)

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Region: chr3:4344988..4359251 View in gBrowse