ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RAPSN
Symbol Alias	RNF205, CMS1D, CMS1E
Approved Name	receptor-associated protein of the synapse
Previous Name	receptor-associated protein of the synapse, 43kD
Name Alias	rapsyn
Location	11p11.2
Position	chr11:47459308-47470730, -
External Links	HGNC: 9863 Entrez Gene: 5913 Ensembl: ENSG00000165917 UCSC: uc001nfi.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 11)

rs_ID	Location	Functional Annotation
rs4282946	Chr11:47456202(Fwd)	downstream_gene_variant
rs10742805	Chr11:47454701(Fwd)	downstream_gene_variant
rs3847503	Chr11:47464519(Fwd)	intron_variant; upstream_gene_variant
rs3740684	Chr11:47468820(Fwd)	intron_variant
rs4752837	Chr11:47465955(Fwd)	intron_variant; upstream_gene_variant
rs3824867	Chr11:47468569(Fwd)	intron_variant
rs7126210	Chr11:47460306(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant; synonymous_variant
rs12419342	Chr11:47468545(Fwd)	intron_variant
rs11039237	Chr11:47456763(Fwd)	downstream_gene_variant
rs7111873	Chr11:47469439(Fwd)	synonymous_variant
rs10742806	Chr11:47456226(Fwd)	downstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043525	positive regulation of neuron apoptotic process	Biological Process		9
GO:0035255	ionotropic glutamate receptor binding	Molecular Function		6
GO:0045211	postsynaptic membrane	Cellular Component		41
GO:0005737	cytoplasm	Cellular Component		690
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0007268	synaptic transmission	Biological Process	TAS[8812503]	96
GO:0007271	synaptic transmission, cholinergic	Biological Process	IGI[18420419]	8
GO:0005856	cytoskeleton	Cellular Component		54
GO:0005886	plasma membrane	Cellular Component		772
GO:0031594	neuromuscular junction	Cellular Component		7
GO:0033130	acetylcholine receptor binding	Molecular Function	IDA[18420419]	2
GO:0008270	zinc ion binding	Molecular Function		323
GO:0030054	cell junction	Cellular Component		77

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RAPSN (count: 11)

Gene Symbol	Pathway Count	Pathway List
ACHE	7	postsynaptic membrane; Golgi apparatus; synaptic transmission; synaptic transmission, cholinergic; plasma membrane; neuromuscular junction; cell junction;
SHANK2	5	ionotropic glutamate receptor binding; postsynaptic membrane; cytoplasm; plasma membrane; cell junction;
CHRNA3	5	postsynaptic membrane; synaptic transmission; synaptic transmission, cholinergic; plasma membrane; cell junction;
CHRNA4	5	postsynaptic membrane; synaptic transmission; synaptic transmission, cholinergic; plasma membrane; cell junction;
CHRNB4	5	postsynaptic membrane; synaptic transmission; synaptic transmission, cholinergic; plasma membrane; cell junction;
GABBR2	5	postsynaptic membrane; cytoplasm; synaptic transmission; plasma membrane; cell junction;
GOPC	5	postsynaptic membrane; cytoplasm; Golgi apparatus; plasma membrane; cell junction;
GRIN2A	5	postsynaptic membrane; synaptic transmission; plasma membrane; zinc ion binding; cell junction;
GRIN2B	5	postsynaptic membrane; synaptic transmission; plasma membrane; zinc ion binding; cell junction;
DTNA	5	cytoplasm; synaptic transmission; plasma membrane; zinc ion binding; cell junction;
SNCA	5	cytoplasm; Golgi apparatus; plasma membrane; zinc ion binding; cell junction;

Genes shared at least 2 KEGG pathways with RAPSN (count: 0)

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Region: chr11:47459308..47470730 View in gBrowse