ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PGA4
Approved Name	pepsinogen 4, group I (pepsinogen A)
Location	11q13
Position	chr11:60989820-61018929, +
External Links	HGNC: 8886 Entrez Gene: 643847 Ensembl: ENSG00000229183
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 4)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005576	extracellular region	Cellular Component	240
GO:0004190	aspartic-type endopeptidase activity	Molecular Function	4
GO:0006508	proteolysis	Biological Process	102
GO:0007586	digestion	Biological Process	13

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04974	Protein digestion and absorption	10	Protein is a dietary component essential for nutritional hom...... Protein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested protein undergoes a complex series of degradative processes following the action of gastric, pancreatic and small intestinal enzymes. The result of this proteolytic activity is a mixture of amino acids and small peptides. Amino acids (AAs) are transported into the enterocyte (intestinal epithelial cell) by a variety of AA transporters that are specific for cationic (basic) AA, neutral AA, and anionic (acidic) AA. Small peptides are absorbed into enterocytes by the PEPT1 transporter. Inside enterocytes peptides are hydrolyzed, and the resulting amino acids are released together with those absorbed by AA transporters into blood via multiple, basolateral, AA transporters. Hydrolysis-resistant peptides, however, are transported out of the cells by a basolateral peptide transporter that has not been identified molecularly. More...

Genes shared at least 5 GO terms with PGA4 (count: 0)

Genes shared at least 2 KEGG pathways with PGA4 (count: 0)

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Region: chr11:60989820..61018929 View in gBrowse