ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GALNT13
Symbol Alias	KIAA1918, GalNAc-T13
Approved Name	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
Name Alias	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
Location	2q24.1
Position	chr2:154728426-155310489, +
External Links	HGNC: 23242 Entrez Gene: 114805 Ensembl: ENSG00000144278 UCSC: uc002tyr.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_12	chr2:153846483-154652950 (NCBI Build 36.1 (hg18))	766494	2q23.3-2q24.1	Gain	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

ID	Name	Type	No. of Genes in ADHDgene
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	Molecular Function	4
GO:0000139	Golgi membrane	Cellular Component	95
GO:0016266	O-glycan processing	Biological Process	5
GO:0016021	integral to membrane	Cellular Component	845
GO:0043687	post-translational protein modification	Biological Process	37
GO:0044267	cellular protein metabolic process	Biological Process	64

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00512	Mucin type O-Glycan biosynthesis	5	O-glycans are a class of glycans that modify serine or threo...... O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis of O-glycans starts from the transfer of N-acetylgalactosamine (GalNAc) to serine or threonine. The first GalNAc may be extended with sugars including galactose, N-acetylglucosamine, fucose, or sialic acid, but not mannose, glucose, or xylose. Depending on the sugars added, there are four common O-glycan core structures, cores 1 through 4, and an additional four, cores 5 though 8. Mucins are highly O-glycosylated glycoproteins ubiquitous in mucous secretions on cell surfaces and in body fluids. Mucin O-glycans can be branched, and many sugars or groups of sugars are antigenic. Important modifications of mucin O-glycans include O-acetylation of sialic acid and O-sulfation of galactose and N-acetylglucosamine. More...

Genes shared at least 5 GO terms with GALNT13 (count: 3)

Gene Symbol	Pathway Count	Pathway List
GALNT1	6	polypeptide N-acetylgalactosaminyltransferase activity; Golgi membrane; O-glycan processing; integral to membrane; post-translational protein modification; cellular protein metabolic process;
GALNT12	6	polypeptide N-acetylgalactosaminyltransferase activity; Golgi membrane; O-glycan processing; integral to membrane; post-translational protein modification; cellular protein metabolic process;
B3GNT6	5	Golgi membrane; O-glycan processing; integral to membrane; post-translational protein modification; cellular protein metabolic process;

Genes shared at least 2 KEGG pathways with GALNT13 (count: 4)

Gene Symbol	Pathway Count	Pathway List
B3GNT6	2	Metabolic pathways; Mucin type O-Glycan biosynthesis;
GALNT1	2	Metabolic pathways; Mucin type O-Glycan biosynthesis;
GALNT12	2	Metabolic pathways; Mucin type O-Glycan biosynthesis;
WBSCR17	2	Metabolic pathways; Mucin type O-Glycan biosynthesis;

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Region: chr2:154728426..155310489 View in gBrowse