ADHDgene Database

Gene Report

Basic Info

Approved Symbol	F2RL2
Symbol Alias	PAR3
Approved Name	coagulation factor II (thrombin) receptor-like 2
Name Alias	proteinase-activated receptor-3
Location	5q13
Position	chr5:75911307-75919259, -
External Links	HGNC: 3539 Entrez Gene: 2151 Ensembl: ENSG00000164220 UCSC: uc003kem.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0016298	lipase activity	Molecular Function		49

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005887	integral to plasma membrane	Cellular Component	TAS[9087410]	220
GO:0005886	plasma membrane	Cellular Component		772
GO:0005576	extracellular region	Cellular Component		240
GO:0005515	protein binding	Molecular Function	IPI[17474147]	910
GO:0030168	platelet activation	Biological Process		38
GO:0016324	apical plasma membrane	Cellular Component		51
GO:0015057	thrombin receptor activity	Molecular Function		1
GO:0009611	response to wounding	Biological Process	TAS[9087410]	9
GO:0007596	blood coagulation	Biological Process		83
GO:0004435	phosphatidylinositol phospholipase C activity	Molecular Function	TAS[9087410]	20

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04080	Neuroactive ligand-receptor interaction	93

Genes shared at least 5 GO terms with F2RL2 (count: 12)

Gene Symbol	Pathway Count	Pathway List
FN1	6	extracellular region; protein binding; platelet activation; apical plasma membrane; response to wounding; blood coagulation;
ADRA2A	5	integral to plasma membrane; plasma membrane; protein binding; platelet activation; blood coagulation;
ADRA2B	5	integral to plasma membrane; plasma membrane; protein binding; platelet activation; blood coagulation;
ADRA2C	5	integral to plasma membrane; plasma membrane; protein binding; platelet activation; blood coagulation;
BDKRB2	5	integral to plasma membrane; plasma membrane; protein binding; lipase activity; phosphatidylinositol phospholipase C activity;
CASR	5	integral to plasma membrane; plasma membrane; protein binding; lipase activity; phosphatidylinositol phospholipase C activity;
CCR5	5	integral to plasma membrane; plasma membrane; protein binding; lipase activity; phosphatidylinositol phospholipase C activity;
GP1BB	5	integral to plasma membrane; plasma membrane; protein binding; platelet activation; blood coagulation;
TRPC3	5	integral to plasma membrane; plasma membrane; protein binding; platelet activation; blood coagulation;
APOA1	5	plasma membrane; extracellular region; protein binding; platelet activation; blood coagulation;
PLCG2	5	plasma membrane; protein binding; platelet activation; blood coagulation; phosphatidylinositol phospholipase C activity;
STXBP3	5	plasma membrane; protein binding; platelet activation; apical plasma membrane; blood coagulation;

Genes shared at least 2 KEGG pathways with F2RL2 (count: 0)

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Region: chr5:75911307..75919259 View in gBrowse